Phenanthrenes and derivatives
Sigma Aldrich Fine Chemicals Biosciences Aristolochic acid I European Pharmacopoeia (EP) Reference Standard | 313-67-7 | MFCD00004996 |
Aristolochic acid I European Pharmacopoeia (EP) Reference Standard | Mol Wt: 341.27 | 313-67-7 | MFCD00004996 |
Medchemexpress LLC Aristolochic acid C | 4849-90-5 | 327.25 | 5 MG
Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid acts as a phospholipase A2 (PLA2) inhibitor, which interferes with cortical microtubule arrays and root growth in Arabidopsis.
- Derivative of Aristolochic acid
- Acts as a phospholipase A2 (PLA2) inhibitor
- Disrupts cortical microtubule arrays
- Interferes with root growth in Arabidopsis
Medchemexpress LLC Aristolochic acid A | 313-67-7 | MFCD00004996 | 99.9% | 10 MG
Aristolochic acid A is a nitrophenanthrene carboxylic acid supplied as a high-purity research reagent for biochemical and cell-based studies. It is commonly used to investigate NF-κB and AP-1 signaling pathways and for mechanistic studies of nephrotoxicity and carcinogenesis.
- High purity (99.9%).
- Molecular formula C17H11NO7; molecular weight 341.27 g/mol.
- Typically supplied as a 10 mg quantity suitable for research use.
- Used in studies of NF-κB and AP-1 inhibition and mechanisms of nephrotoxicity and carcinogenicity.
- Handle as a toxic and carcinogenic compound with appropriate safety precautions.
Medchemexpress LLC Aristolochic acid Va | 108779-46-0 | 357.27 | 1 MG
Aristolochic acid Va is a natural compound isolated from *Aristolochia* plants. This high-purity compound is intended for research use only, supporting a wide range of studies in natural product chemistry and biological activity.
- Natural compound isolated from Aristolochia plants.
- Suitable for various research applications.
- High purity for reliable experimental results.
- Available in multiple sizes for research flexibility.
Medchemexpress LLC Aristolochic acid D (Aristolochic acid-IVa) | 17413-38-6 | 357.27 | 1 ML
Aristolochic acid D (Aristolochic acid-IVa) is an orally active inhibitor of PDE2 (IC50: 4.673 μM) and CDK2 (IC50: 25 μM) that is isolated from Aristolochia indica L. It demonstrates anti-inflammatory activity and is considered non-carcinogenic and non-nephrotoxic. This compound is suitable for research related to inflammation and tumor-related diseases.
- Orally active PDE2 inhibitor (IC50: 4.673 μM).
- CDK2 inhibitor (IC50: 25 μM).
- Isolated from Aristolochia indica L.
- Exhibits anti-inflammatory activity.
- Non-carcinogenic.
- Non-nephrotoxic.
- Useful in research for inflammation and tumor-related diseases.
Medchemexpress LLC Hypericin | 548-04-9 | 504.443 | 1 MG
Hypericin is a naturally occurring substance found in Hypericum perforatum L. It functions as an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase, and CYP (cytochrome P450). It exhibits antitumor, antiviral, and antidepressive activities, and can induce apoptosis.
- Inhibits PKC (protein kinase C)
- Inhibits MAO (monoaminoxidase)
- Inhibits dopamine-beta-hydroxylase
- Inhibits reverse transcriptase
- Inhibits telomerase
- Inhibits CYP (cytochrome P450)
- Shows antitumor activity
- Shows antiviral activity
- Shows antidepressive activity
- Induces apoptosis
- Relevant for infection research
- Relevant for neurological disease research
- Relevant for cancer research
Apexbio Technology LLC Hypericin 548-04-9 10mg
Hypericin (CAS 548-04-9) is a small-molecule inhibitor targeting protein kinase C (PKC) and monoamine oxidase (MAO) It acts to selectively inhibit these enzymes thereby regulating cellular signal transduction pathways related to cell proliferation and apoptosis Hypericin exerts its biological activity primarily through selective inhibition of PKC In in vitro assays hypericin demonstrates an inhibitory profile with IC50 values against PKC ranging from approximately 100 to 250 nM depending on assay conditions Based on these pharmacological properties hypericin holds research potential in oncology virology and neuroscience
eMolecules Chem-Impex Malonic acid anhydrous 25kg 272385283 02873 0 000 141-82-2 104 061 C3H4O4
Chem-Impex Malonic acid anhydrous 25kg 272385283 02873 0 000 141-82-2 104 061 C3H4O4
eMolecules Apollo Scientific US - Building Blocks Hexakis(2 2 3 3-tetrafluoropropoxy)phosphazene 250mg 398010245 PC0874 0 000 58943-98-9 MFCD00798140 921 240 C18H18F24N3O6P3
Apollo Scientific US - Building Blocks Hexakis(2 2 3 3-tetrafluoropropoxy)phosphazene 250mg 398010245 PC0874 0 000 58943-98-9 MFCD00798140 921 240 C18H18F24N3O6P3
Medchemexpress LLC Vilazodone hydrochloride | 163521-08-2 | 100.7% | C26H28ClN5O2 | 200 MG
Vilazodone hydrochloride is a serotonin transporter (SER) inhibitor and 5-HT1A receptor partial agonist. This product is for research use only.
- Serotonin transporter (SER) inhibitor
- 5-HT1A receptor partial agonist
- Ships at room temperature
- Store at 4°C, sealed, away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
Medchemexpress LLC Prazosin (hydrochloride) | 19237-84-4 | 99.9% | 200 MG
Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist. It is utilized in research for high blood pressure and alcohol use disorders. The compound effectively inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC50 of 0.15 nM and also inhibits organic cation transporters OCT-1 and OCT-3 with IC50s of 1.8 and 13 μM, respectively.
- Acts as a CNS-active α1-adrenergic receptor antagonist
- Used in research for high blood pressure
- Used in research for alcohol use disorders
- Potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux
- Inhibits organic cation transporters OCT-1 and OCT-3
Medchemexpress LLC 6-aminochrysene | 2642-98-0 | MFCD00003699 | 99.7% | 243.30 g/mol | C18H13N | 1 ML
6-Aminochrysene is an aromatic amine (CAS 2642-98-0) supplied as a ready-to-use 10 mM solution in DMSO. Provided in a 1 mL vial for research use, the material is characterized by a defined molecular weight and high purity suitable for biochemical, metabolic, and toxicology studies.
- Ready-to-use 10 mM solution in DMSO.
- Supplied in a 1 mL vial for small-scale experiments.
- High purity (99.7%) suitable for analytical applications.
- Molecular weight 243.30 g/mol for stoichiometric calculations.
- Appropriate for biochemical and metabolic study workflows.
Medchemexpress LLC 6-aminochrysene | 2642-98-0 | MFCD00003699 | 99.7% | 243.30 g/mol | C18H13N | 50 MG
6-Aminochrysene is an aromatic amine research compound (CAS 2642-98-0) used in laboratory studies. The light yellow solid has molecular formula C18H13N and a molecular weight of 243.30 g/mol. The supplier lists high purity, DMSO solubility data, storage recommendations for powder and solutions, and multiple small pack sizes for research use.
- Light yellow to yellow solid appearance.
- Molecular formula C18H13N and molecular weight 243.30 g/mol.
- High purity (99.7%).
- Soluble in DMSO (100 mg/mL); sonication recommended.
- Recommended storage conditions provided for powder and in-solution forms.
- Available in small research pack sizes, including 50 mg.